Working inexperienced in this new realm of vaccine technology, the same question arose with a second amplifier. The Johnson and Johnson Janssen Viral Vaccine (J&J) came in third in the vaccine race. It protects against the main criteria of prevention of serious illness, hospitalization and death, but not equally. The issue of the mix was actually resolved in the news last October-November, after the CDC approved the second booster. A very perceptive person sent me an informative study of the research done to test the antibody responses in two small groups of people who received the first two sets of initial vaccine vaccines, 28 who received Moderna and 45 who received Pfizer / BioNTech. They were all young female doctors. The test was done only about 1 month after the second dose, not for many months to be tested for antibody loss.
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Both vaccines produced strong levels of neutralizing antibodies, the kind that bind to the virus and prevent it from infecting cells. The Pfizer vaccine produced more Ig (immunoglobulin) G and IgM antibodies, which are found in most bloodstream microbial infections. The Moderna vaccine stimulated relatively high levels of IgA antibodies, which are generally found on the surfaces of mucous membranes, such as the airways of the throat and lungs, the initial port of entry for SARS-Cov2 viruses. Moderna also induced higher levels of antibodies that activate natural white blood cell killer lymphocytes to attack the virus directly, and other antibodies that stimulate neutrophil white blood cells, which swallow and kill invaders. These differences could complement each other enough to extend the spectrum of immunity beyond just one brand. This study will most likely be the subject of further research. An April 2 article in C / NET, a wellness-labeled online media site, addressed the issue. The real CDC was set up last October to merge vaccine brands. The Pfizer is the same amount of material injected, 30 micrograms, as the initial shots. Moderna’s is now 50 micrograms, half of the 100 micrograms that were in the first shots. A professor of preventive medicine at Vanderbilt University said, “The most important reason is that the blend offers benefits to the enhanced immune response and, therefore, expected enhanced protection.” A CDC report published last week found that people who received two doses of the J&J vaccine were less protected from emergency or emergency care visits (54%) due to COVID compared with those who received a single dose of J&J plus a booster mRNA (73%). % effective. ). Individuals receiving 3 doses of an mRNA vaccine were 83% protected from emergency visits. This makes it easy to secure a second amplifier if your site has only one brand. It does not matter who you shoot with. For those who have had some reaction from the original Moderna series, there should be less concern about the half dose. Vaccination is not a perfect shield, but it is the best defense we have against this viral parabola and the prevention against the emergence of new variants. Fortunately, this information can shed light on and alleviate the concerns that potential patients may have about taking a shot with more “stuff.” And alleviate any worries about getting the right “materials” because any of the available vaccines are labyrinthine. As far as “mixing and matching” is concerned, I have never found any difficulty in testing for the various brands of dark chocolate that I mix and match in personal “therapeutic” postprandial (after dinner) studies. I have not felt any negative effects from any particular type. It’s just that they all cause the same side effect that makes my clothes shrink. Dr. Bures, a retired dermatologist, has worked for Winona, La Crosse, Viroqua and Red Wing since 1978. He also plays the clarinet in the Winona Municipal Band and in some dixieland groups. And he enjoys a good pun. Receive local news in your inbox!
